We are currently investigating new catalytic strategies
for the selective modification of C–H bonds in complex molecules, to enable precision molecular editing
as a drug discovery strategy.
Nitrogen-containing heterocyclic are common in pharmaceuticals and are a defining feature of alkaloid natural products. We seek to develop fundamentally new synthetic approaches with broad applicability.
Learn moreWe have received a new R35 (MIRA) award from the NIH! It will support projects on new C–H functionalization and Diels-Alder reactions.
PhD student Anna Davis was selected from among all poster presenters to give a short talk at the Organic Reactions & Processes GRC. Congrats!
PhD student Ian Winchester has been awarded a training grant fellowship from the UVA Comprehensive Cancer Center. Congrats!
E. N. Cook, A. E. Davis, M. K. Hilinski, C. W. Machan, J. Am. Chem. Soc. 2024, 146, 7931-7935.
P. L. Hahn, J. M. Lowe, Y. Xu, K. L. Burns, M. K. Hilinski, ACS Catal. 2022, 12, 4302-4309.
A. E. Davis, J. M. Lowe, M. K. Hilinski, Chem. Sci. 2021, 12, 15947-15952.
S. L. Johnson and M. K. Hilinski, e-EROS Encyclopedia of Reagents for Organic Synthesis [Online], John Wiley & Sons, 2020.
M. E. Rotella, R. M. B. Dyer, M. K. Hilinski, and O. Gutierrez, ACS Catal., 2020, 10, 897-906.
J. E. Laudenschlager, L. A. Combee, M. K. Hilinski, Org. Biomol. Chem. 2019, 17, 9413-9417.
S. L. Johnson and M. K. Hilinski, J. Org. Chem. 2019, 84, 8589-8595.
L. A. Combee, S. L. Johnson, J. E. Laudenschlager, M. K. Hilinski, Org. Lett. 2019, 21, 2307-2311.
S. L. Johnson, L. A. Combee, M. K. Hilinski, Synlett 2018, 29, 2331-2336.
R. M. B. Dyer, P. L. Hahn, M. K. Hilinski, Org. Lett. 2018, 20, 2011-2014.
L. A. Combee, B. Raya, D. Wang, M. K. Hilinski, Chem. Sci. 2018, 9, 935-939.
W. G. Shuler, S. L. Johnson, M. K. Hilinski, Org. Lett. 2017, 19, 4790-4793.
D. Wang, W. G. Shuler, C. J. Pierce, M. K. Hilinski, Org. Lett. 2016, 18, 3826-3829.
W. G. Shuler, L. A. Combee, I. D. Falk, M. K. Hilinski, Eur. J. Org. Chem. 2016, 3335–3338.
C. J. Pierce, M. K. Hilinski, Org. Lett. 2014, 16, 6504–6507.